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HerBalance™


BC4

HerBalance™ Natural Menopause Support (60 capsules)
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What is HerBalance™?
HerBalance™ is a natural formula designed to support well-being in and lessen some of the symptoms commonly associated with menopause. HerBalance™ contains Novasoy® soy isoflavones from non-genetically modified soy, red clover isoflavones, black cohosh, damiana leaf and licorice root. Clinical studies show that soy isoflavones, like Novasoy®, lower the incidence of hot flashes. Additional soy isoflavones from Novasoy®; may help maintain strong and healthy bones and may help improve cognitive function.

Why Is Our HerBalance™ Better?
Our HerBalance™ is a blend of the highest quality natural menopause support supplements providing a combination time-tested ingredients that may help support premenopausal, menopausal and peremenopausal women.

Who Should Consider HerBalance™?
Women suffuring from the symptoms of premenopause, menopause or peremenopause. The American Menopause Society, recommends the use of Black Cohosh, dietary isoflavones (such as soy and red clover), and Vitamin E for the treatment of mild vasomotor symptoms.14

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HerBalance™ Natural Menopause Support (60 capsules)   BC4   (30 Day Supply)
HerBalance™ Natural Menopause Support (60 capsules)
       
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HerBalance™ is a nutritional supplement designed specifically to help ease some of the symptoms associated with menopause. HerBalance™ is a safe, natural combination of the highest quality natural ingredients that both modern science and traditional medicine indicate may promote well-being during menopause.

Novasoy® Standardized Soybean Extract

Novasoy® is a rich source of soy isoflavones. Clinical research shows that soy isoflavones, like Novasoy reduce the number and frequency of menopausal symptoms such as hot flashes. Other studies have indicated that soy isoflavones may relieve night sweats and vaginal dryness.15,23,32,35 As well Novasoy® helps maintain strong and healthy bones by helping to preserve bone density and bone mineral content.20,26,33 Preliminary research suggests soy isoflavones may help keep arteries strong, and healthy arteries contribute to a healthy cardiovascular system. 30 Novasoy® may help improve cognitive function. Soy isoflavones are one of the natural products that the North American Menopause Society recommends taking to reduce mild hot flashes.14

Red Clover Extract:

Red Clover is also a rich source of isoflavones. Some studies have indicated that red clover may have a positive effect on HDL cholesterol and triglyceride levels in post menopausal women.46,47,51Like soy isoflavones, red clover isoflavones may be effective in reducing hot flashes59 and they may be beneficial to the heart.56,57,58 It is also one of the natural products that the North American Menopause Society recommends taking to reduce mild hot flashes.14

Black Cohosh Extract:

Black Cohosh is a plant native to eastern North America and may be helpful with the symptoms commonly associated with menopause, particularly hot flashes, menstrual cramps, changes to the vaginal lining and even low mood. It use as a Traditional Medicine dates back hundreds, perhaps thousands of years to the early Native American groups that first noted its potential benefits. Black cohosh is among the list of natural products that the North American Menopause Society recommends taking to reduce mild hot flashes.14

Damiana Leaf:

Damiana is a plant native to southern North American, the Caribbean, and Central and South America. Like Black Cohosh it is a traditional folk remedy with a long history of use as a treatment of menopausal hot flashes  and as an aphrodisiac, for sexual disfunction, headaches and low energy.62,63 There is little scientific evidence to support the claims, however believers swear by it. The German Commision E studies found no know side effects or contridications.63

Licorice Root:

One of the most popular herbal remedies in the world. As a traditional remedy lots of benefits are attributed to this herb. It's used as an anti-inflammatory, anti-spasmatic and it provides estogen-like hormone effects.64,66






Interactions
HerBalance™ should not be used if you are pregnant, think you are pregnant or plan to be pregnant in the near future. It is strictly for premenopausal, menopausal or peremenopausal  women. The North American Menopause Society, recommends the use of Black Cohosh, dietary isoflavones (such as soy and red clover), and Vitamin E for the treatment of mild vasomotor symptoms.14 We however, recommend women at risk of, or with a history of, estrogen-sensitive breast cancer use caution when taking these products. Some studies have indicated that soy isoflavones & red clover may induce cell proliferation.16 Other studies have not been able to establish a link, while the jury is out, we recommend using caution while taking soy, red clover and the like.


Label Facts


Supplement Facts
Serving Size: 2 Capsules
Servings per container: 30
Amount Per Serving % Daily Value
Damiana Leaf 200 mg
Licorice Root 200 mg
NovaSoy® Standardized Soybean Extract‡ 150 mg
     Soy Isoflavones (yield) 60 mg
Black Cohosh Extract 2.5% 100 mg
Red Clover Extract 4:1 100 mg
†Daily value not established.

   Other ingredients: Cellulose (plant fiber), magnesium stearate (vegetable source).
   ‡From Non-GMO (Genetically Modified) Soy


Allergen Warning

Contains soy product

Dietary Restrictions

Vegetarian capsule used and a vegetarian formula.  Vegetarian capsule used and a vegetarian formula.

References

Black Cohosh References / Additional Resources
  1. Blumenthal, Mark; Busse, Werner R; Goldberg, Alicia; Gruenwald, Joerg, PhD; Hall, Tara; Riggins, Chance W.; Rister, Robert S., Eds, Klein, Sigrid, PhD; Rister, Robert S, Trans, Tyler, VarroE, PhD, ScD. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council, 1998.
  2. Blumenthal, Mark; Goldberg, Alicia; Brinckmann, Josef, Eds,; Tyler, VarroE, PhD, ScD. Herbal Medicine: Expanded Commission E Monographs. American Botanical Council, 2000.
  3. Einer-Jensen N, Zhao J, Andersen KP, Kristoffersen KMaturitas. Cimicifuga and Melbrosia lack oestrogenic effects in mice and rats. 1996 Oct;25(2):149-53
  4. Gruenwald, Joerg, PhD; Brendler, Thomas, BA; Jaenicke, Christof, MD. PDR for Herbal Medicines. Medical Economics Company, 1998.
  5. Korn W.D. Six-Month Oral Toxicity Study with Remifemin-Granulate in Rats Followed by an 8-Week Recovery Period (Hannover, Germany: International Bioresearch, 1991).
  6. Lieberman S. A review of the effectiveness of Cimicifuga racemosa (black cohosh) for the symptoms of menopause. J Womens Health 1998 Jun;7(5):525-9
  7. Liske E. Therapeutic efficacy and safety of Cimicifuga racemosa for gynecologic disorders. Adv Ther 1998 Jan-Feb;15(1):45-53
  8. Murray, Michael, ND, Pizzorno, Joseph, ND. Encyclopedia of Natural Medicine, second ed. Prima Publishing, Rocklin. 1999.
  9. Nesselhut, T.; Borth, S.; and Kuhn, W. "Influence of Cimicifuga Racemosa Extracts with Estrogen-like Activity on the in Vitro Proliferation of Mamma Carcinoma Cells," Arch Gynecol Obstet 254 (1993): 817-8.
  10. Stolze, H. "An Alternative to Treat Menopausal Complaints," Gyne 3 (1982): 14-6.
Double-Blind Trials
  1. Duker EM, Kopanski L, Jarry H, Wuttke W. Effects of extracts from Cimicifuga racemosa on gonadotropin release in menopausal women and ovariectomized rats. Planta Med 1991 Oct;57(5):420-4
  2. Stoll, W. 1987 Phytopharmacon influences atrophic vaginal epithelium: Double blind study-cimicifuga vs. estrogenic substances. Therapeuticum 1:23-31.
  3. Warnecke, G. "Influencing Menopausal Symptoms with a Phytotherapeutic Agent," Med Welt 36 (1985): 871-4.
Soy Isoflavones References / Additional Resources
  1. Treatment of menopause-associated vasomotor symptoms: position statement of The North American Menopause Society. Menopause, 2004. 11(1): p. 11-33.
  2. Balk, J.L., et al., A pilot study of the effects of phytoestrogen supplementation on postmenopausal endometrium. J Soc Gynecol Investig, 2002. 9(4): p. 238-42.
  3. Bodinet, C. and J. Freudenstein, Influence of marketed herbal menopause preparations on MCF-7 cell proliferation. Menopause, 2004. 11(3): p. 281-9.
  4. Boker, L.K., et al., Intake of dietary phytoestrogens by Dutch women. J Nutr, 2002. 132(6): p. 1319-28.
  5. Burke, G.L., et al., Soy protein and isoflavone effects on vasomotor symptoms in peri- and postmenopausal women: the Soy Estrogen Alternative Study. Menopause, 2003. 10(2): p. 147-53.
  6. Cassidy, A., Potential risks and benefits of phytoestrogen-rich diets. Int J Vitam Nutr Res, 2003. 73(2): p. 120-6.
  7. Chen, Y.M., et al., Beneficial effect of soy isoflavones on bone mineral content was modified by years since menopause, body weight, and calcium intake: a double-blind, randomized, controlled trial. Menopause, 2004. 11(3): p. 246-54.
  8. Chiechi, L.M., et al., The effect of a soy rich diet on the vaginal epithelium in postmenopause: a randomized double blind trial. Maturitas, 2003. 45(4): p. 241-6.
  9. Cuevas, A.M., et al., Isolated soy protein improves endothelial function in postmenopausal hypercholesterolemic women. Eur J Clin Nutr, 2003. 57(8): p. 889-94.
  10. Faure, E.D., P. Chantre, and P. Mares, Effects of a standardized soy extract on hot flushes: a multicenter, double-blind, randomized, placebo-controlled study. Menopause, 2002. 9(5): p. 329-34.
  11. Foth, D. and F. Nawroth, Effect of soy supplementation on endogenous hormones in postmenopausal women. Gynecol Obstet Invest, 2003. 55(3): p. 135-8.
  12. Gallagher, J.C., et al., The effect of soy protein isolate on bone metabolism. Menopause, 2004. 11(3): p. 290-8.
  13. Ho, S.C., et al., Soy protein consumption and bone mass in early postmenopausal Chinese women. Osteoporos Int, 2003. 14(10): p. 835-42.
  14. Huntley, A.L. and E. Ernst, Soy for the treatment of perimenopausal symptoms--a systematic review. Maturitas, 2004. 47(1): p. 1-9.
  15. Jayagopal, V., et al., Beneficial effects of soy phytoestrogen intake in postmenopausal women with type 2 diabetes. Diabetes Care, 2002. 25(10): p. 1709-14.
  16. Kritz-Silverstein, D., et al., Isoflavones and cognitive function in older women: the SOy and Postmenopausal Health In Aging (SOPHIA) Study. Menopause, 2003. 10(3): p. 196-202.
  17. Lucas, E.A., et al., Soy isoflavones prevent ovariectomy-induced atherosclerotic lesions in Golden Syrian hamster model of postmenopausal hyperlipidemia. Menopause, 2003. 10(4): p. 314-21.
  18. Messina, M.J., Soy foods and soybean isoflavones and menopausal health. Nutr Clin Care, 2002. 5(6): p. 272-82.
  19. Messina, M. and C. Hughes, Efficacy of soyfoods and soybean isoflavone supplements for alleviating menopausal symptoms is positively related to initial hot flush frequency. J Med Food, 2003. 6(1): p. 1-11.
  20. Moeller, L.E., et al., Isoflavone-rich soy protein prevents loss of hip lean mass but does not prevent the shift in regional fat distribution in perimenopausal women. Menopause, 2003. 10(4): p. 322-31.
  21. Morelli, V. and C. Naquin, Alternative therapies for traditional disease states: menopause. Am Fam Physician, 2002. 66(1): p. 129-34.
  22. Nagata, C., et al., Hot flushes and other menopausal symptoms in relation to soy product intake in Japanese women. Climacteric, 1999. 2(1): p. 6-12.
  23. Nicholls, J., et al., Effects of soy consumption on gonadotropin secretion and acute pituitary responses to gonadotropin-releasing hormone in women. J Nutr, 2002. 132(4): p. 708-14.
  24. Penotti, M., et al., Effect of soy-derived isoflavones on hot flushes, endometrial thickness, and the pulsatility index of the uterine and cerebral arteries. Fertil Steril, 2003. 79(5): p. 1112-7.
  25. Steinberg, F.M., et al., Soy protein with isoflavones has favorable effects on endothelial function that are independent of lipid and antioxidant effects in healthy postmenopausal women. Am J Clin Nutr, 2003. 78(1): p. 123-30.
  26. Suthar, A.C., M.M. Banavalikar, and M.K. Biyani, Pharmacological activities of Genistein, an isoflavone from soy (Glycine max): part II--anti-cholesterol activity, effects on osteoporosis & menopausal symptoms. Indian J Exp Biol, 2001. 39(6): p. 520-5.
  27. Tice, J.A., et al., Phytoestrogen supplements for the treatment of hot flashes: the Isoflavone Clover Extract (ICE) Study: a randomized controlled trial. Jama, 2003. 290(2): p. 207-14.
  28. Uesugi, T., Y. Fukui, and Y. Yamori, Beneficial effects of soybean isoflavone supplementation on bone metabolism and serum lipids in postmenopausal japanese women: a four-week study. J Am Coll Nutr, 2002. 21(2): p. 97-102.
  29. Wu, A.H., et al., Soy intake and other lifestyle determinants of serum estrogen levels among postmenopausal Chinese women in Singapore. Cancer Epidemiol Biomarkers Prev, 2002. 11(9): p. 844-51.
  30. Yamamoto, S., et al., Soy, isoflavones, and breast cancer risk in Japan. J Natl Cancer Inst, 2003. 95(12): p. 906-13.
Red Clover References / Additional Resources
  1. Barnes, S., Phyto-oestrogens and osteoporosis: what is a safe dose? Br J Nutr, 2003. 89 Suppl 1: p. S101-8.
  2. Bodinet, C. and J. Freudenstein, Influence of marketed herbal menopause preparations on MCF-7 cell proliferation. Menopause, 2004. 11(3): p. 281-9.
  3. Campbell, M.J., et al., Effect of red clover-derived isoflavone supplementation on insulin-like growth factor, lipid and antioxidant status in healthy female volunteers: a pilot study. Eur J Clin Nutr, 2004. 58(1): p. 173-9.
  4. Clifton-Bligh, P.B., et al., The effect of isoflavones extracted from red clover (Rimostil) on lipid and bone metabolism. Menopause, 2001. 8(4): p. 259-65.
  5. Fugh-Berman, A. and F. Kronenberg, Red clover (Trifolium pratense) for menopausal women: current state of knowledge. Menopause, 2001. 8(5): p. 333-7.
  6. Garcia-Martinez, M.C., et al., Phytoestrogens increase the capacity of serum to stimulate prostacyclin release in human endothelial cells. Acta Obstet Gynecol Scand, 2003. 82(8): p. 705-10.
  7. Howes, J.B., et al., The effects of dietary supplementation with isoflavones from red clover on the lipoprotein profiles of post menopausal women with mild to moderate hypercholesterolaemia. Atherosclerosis, 2000. 152(1): p. 143-7.
  8. Howes, J.B., et al., Effects of dietary supplementation with isoflavones from red clover on ambulatory blood pressure and endothelial function in postmenopausal type 2 diabetes. Diabetes Obes Metab, 2003. 5(5): p. 325-32.
  9. Huntley, A.L. and E. Ernst, A systematic review of herbal medicinal products for the treatment of menopausal symptoms. Menopause, 2003. 10(5): p. 465-76.
  10. Kronenberg, F. and A. Fugh-Berman, Complementary and alternative medicine for menopausal symptoms: a review of randomized, controlled trials. Ann Intern Med, 2002. 137(10): p. 805-13.
  11. Liu, J., et al., Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms. J Agric Food Chem, 2001. 49(5): p. 2472-9.
  12. Moyad, M.A., Complementary/alternative therapies for reducing hot flashes in prostate cancer patients: reevaluating the existing indirect data from studies of breast cancer and postmenopausal women. Urology, 2002. 59(4 Suppl 1): p. 20-33.
  13. Nestel, P.J., et al., Isoflavones from red clover improve systemic arterial compliance but not plasma lipids in menopausal women. J Clin Endocrinol Metab, 1999. 84(3): p. 895-8.
  14. Teede, H.J., et al., Isoflavones reduce arterial stiffness: a placebo-controlled study in men and postmenopausal women. Arterioscler Thromb Vasc Biol, 2003. 23(6): p. 1066-71.
  15. Tice, J.A., et al., Phytoestrogen supplements for the treatment of hot flashes: the Isoflavone Clover Extract (ICE) Study: a randomized controlled trial. Jama, 2003. 290(2): p. 207-14.
  16. van de Weijer, P.H. and R. Barentsen, Isoflavones from red clover (Promensil) significantly reduce menopausal hot flush symptoms compared with placebo. Maturitas, 2002. 42(3): p. 187-93.
  17. Wuttke, W., et al., Phytoestrogens for hormone replacement therapy? J Steroid Biochem Mol Biol, 2002. 83(1-5): p. 133-47.
  18. Wuttke, W., et al., Phytoestrogens: endocrine disrupters or replacement for hormone replacement therapy? Maturitas, 2003. 44 Suppl 1: p. S9-20.
Additional Resources
  1. Benghuzzi, H., et al., The effects of sustained delivery of diosgenin on the adrenal gland of female rats. Biomed Sci Instrum, 2003. 39: p. 335-40.
  2. Blumenthal, Mark; Busse, Werner R; Goldberg, Alicia; Gruenwald, Joerg, PhD; Hall, Tara; Riggins, Chance W.; Rister, Robert S., Eds, Klein, Sigrid, PhD; Rister, Robert S, Trans, Tyler, VarroE, PhD, ScD. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council, 1998.
  3. Griffith, H. Winter. M.D., Vitamins, Herbs, Minerals, & Supplements: The Complete Guide. Fisher Books, 1998.
  4. Komesaroff, P.A., et al., Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric, 2001. 4(2): p. 144-50.
  5. Murray, Michael, N.D., The Pill Book Guide to Natural Medicines. Bantam Books, 2002.
  6. Rosenberg Zand, R.S., D.J. Jenkins, and E.P. Diamandis, Effects of natural products and nutraceuticals on steroid hormone-regulated gene expression. Clin Chim Acta, 2001. 312(1-2): p. 213-9.
  7. Zava, D.T., C.M. Dollbaum, and M. Blen, Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med, 1998. 217(3): p. 369-78.


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