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Horsechestnut Extract
HC1
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IN STOCK - YES
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What is Horsechestnut Extract?
Horsechestnut extract is the extract of the seed of Aesculus hippocastanum. A long time folk remedy for varicose veins and hemorrhoids, Horsechestnut Extract works. Responsible for this herb's vascular-tightening effect is the mixture of triterpene glycosides referred to as "aescin". Aescin has been studied against placebo and been shown to reduce vascular filtration and to relieve common symptoms of chronic vascular insufficiency, such as pain and swelling of the legs and cramping.
Who Should Consider Horsechestnut Extract?
A long time folk remedy for varicose veins and hemorrhoids, Horsechestnut Extract works! Responsible for this herb's vascular-tightening effect is the mixture of triterpene glycosides referred to as "aescin". Aescin has been studied against placebo and been shown to reduce vascular filtration and to relieve common symptoms of chronic vascular insufficiency, such as pain and swelling of the legs, pruritis (itching) and cramping of the calf muscles. Aescin works by inhibiting the activity of (lysosomal) enzymes which are particularly active in the bodies of people who suffer from chronic vascular insufficiency.5 These enzymes break down mucopolysaccharides in the region of the capillary walls. By inhibiting their activity, aescin reduces capillary permeability (leakiness) and the resulting edema1 and pain.
One study comparing the effectiveness of aescin to compression stockings and using a placebo control group showed nearly identical results between the compression stocking group and those who took the Horsechestnut Extract!2 Those who use them know: compression stockings are inconvenient, expensive and unattractive - try Horsechestnut Seed Extract.
We strongly recommend the use of OPC Grape Seed Extract in combination with this product, because of its demonstrated ability to strengthen vascular walls.
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What is Horsechestnut Extract?
It is the extract of the seed of Aesculus hippocastanum.
Horsechestnut Extract Instructions
Recommended supplementation is extract equivalent to 50mg aescin, 3/day.
Our Horsechestnut provides 50mg aescin per capsule.
Our Horsechestnut Extract
Horsetail (Equisetum arvense) has been added to assist in the reduction of edema commonly associated with chronic vascular insufficiency.
Citrus bioflavonoids have also been added to help strengthen the blood vessel walls (please see our Grape Seed Extract page for more information on vascular support).
We strongly recommend the use of OPC Grape Seed Extract in combination with this product, because of its demonstrated ability to strengthen vascular walls.
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Label Facts
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Supplement Facts
Serving Size: 1 Capsules
Servings per container: 90 |
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Amount Per Serving |
% Daily Value |
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| Horsechestnut extract (seed), 20% Aescin |
250 mg |
† |
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| Calandula (flower) |
100 mg |
† |
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Other ingredients: Millet, gelatin (capsule).
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Dietary Restrictions
 Gelatin capsule used with a vegetarian formula.
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References
Horsechestnut Extract References / Additional Resources
- Bisler H et al., "Effects of horse-chestnut seed extract on transcapillary filtration in chronic venous insufficiency" Dtsch Med Wochenschr 111(35):1321-9, 1986.
- Diehm et al., "Comparison of Leg Compression Stocking and Oral Horse Chestnut Seed Extract Therapy in patients with Chronic Venous Insufficiency," Lancet 347:292-4, 1996.
- Facino, R. M., M. Carini, R. Stefani, G. Aldini and L. Saibene (1995). "Anti-elastase and anti-hyaluronidase activities of saponins and sapogenins from Hedera helix, Aesculus hippocastanum, and Ruscus aculeatus: factors contributing to their efficacy in the treatment of venous insufficiency." Arch Pharm (Weinheim) 328(10): 720-4.
- Krysel HW, Nissen HP, Enghoffer E. "A possible role of lysosomal enzymes in the pathogenesis of varicosis and the reduction in their serum activity by venostasin," VASA 12:377-82, 1983.
- Pittler, M. H. and E. Ernst (1998). "Horse-chestnut seed extract for chronic venous insufficiency. A criteria-based systematic review." Arch Dermatol 134(11): 1356-60.
Double-Blind Placebo-Controlled Trials
- Bisler, H., R. Pfeifer, N. Kluken and P. Pauschinger (1986). "[Effects of horse-chestnut seed extract on transcapillary filtration in chronic venous insufficiency]." Dtsch Med Wochenschr 111(35): 1321-9.
- Diehm, C., D. Vollbrecht, K. Amendt and H. U. Comberg (1992). "Medical edema protection--clinical benefit in patients with chronic deep vein incompetence. A placebo controlled double blind study." Vasa 21(2): 188-92.
- Pittler, M. H. and E. Ernst (1998). "Horse-chestnut seed extract for chronic venous insufficiency. A criteria-based systematic review." Arch Dermatol 134(11): 1356-60.
- Rehn, D., M. Unkauf, P. Klein, V. Jost and P. W. Lucker (1996). "Comparative clinical efficacy and tolerability of oxerutins and horse chestnut extract in patients with chronic venous insufficiency." Arzneimittelforschung 46(5): 483-7.
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