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Lycopene


LP2

Lycopene, 10mg (90 softgels)
IN STOCK - YES
What is Lycopene?
As a major carotenoid antioxidant in human blood, lycopene protects against oxidative damage to lipids, proteins, and DNA. Our lycopene is a natural tomato extract rich in lycopene and other important bioactive phytochemicals. Lycopene from tomatoes, has been shown to have superior bioavailability making it an excellent choice for antioxidant health protection.

Why Is Our Lycopene Better?
Our lycopene is a natural tomato extract. Standardization assures you that each and every capsule of our lycopene contains the same quantity of lycopene in addition to a natural ratio of all the other important bioactive phytonutrients found in the tomato oleoresin.

The potential health benefits of a dietary ingredient are dependent upon the ability of the body to absorb and utilize the ingredient.


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Lycopene, 10mg (90 softgels)   LP2   (90 Day Supply)
Lycopene, 10mg (90 softgels)
       
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Background Information on Lycopene:

What the heck is an antioxidant and why should I care? An antioxidant is a substance that reduces the oxidative damage caused by free radicals. Free radicals are unstable atoms or molecules with at least one unpaired electron. These atoms or molecules with unpaired electrons go looking for another electron to pair up with. If they find an electron, they take it. That makes them stable now, but it makes the atoms or molecules that they took the electron from, unstable. This makes for a new, Free Radical. Additionally, the serious damage from free radicals seems to come in the act of searching for, piercing into and taking electrons from cells. This “oxidization” activity damages cell structures, particularly the cellular plasma membranes. Plasma cell membranes are natural gate keepers for cells, deciding what comes and goes within the cell. Damaging the plasma cell membrane and/or having the presence of free radicals in the cell, can damage the cell’s ability to generate energy (in the mitochondria organelles), damage the cell’s nucleus or damage the cell’s DNA. Through this process the use and movement of nutrients, oxygen, water, waste products and toxins can also be hindered.

So how do we stop, or reduce the activities or impacts of free radicals? The answer is the aforementioned Antioxidants. Antioxidants inhibit the oxidization and/or the reactions that are caused by free radicals and by doing so, limit or stop the effects of free radicals.

Numerous scientific studies have concluded that by consuming foods and supplements which are rich in antioxidant properties, the incidence of diseases associated with the consequences of Free Radical oxidization can be reduced. This does not mean that these diseases can be cured, treated or prevented. Rather, it means that in scientific studies, people who consumed significant levels of antioxidants may have lower incidences of certain ailments.

Side Effects
No known side effects, but studies in pregnant or nursing women have not been done. Women who are pregnant or nursing should stick to natural sources of lycopene, such as tomatoes and green/yellow vegetables.


Label Facts

  Lycopene, 10mg, 90 Softgels:
Supplement Facts
Serving Size: 1 Softgels
Servings per container: 90
Amount Per Serving % Daily Value
Lycopene (from Tomato) 10 mg
†Daily value not established.

   Other ingredients: Gelatin softgel capsule (gelatin, vegetable glycerin, purified water), soybean oil, corn oil, gelatin, vegetable glycerin, and yellow beeswax.



Allergen Warning

Contains soy and tomato products

Dietary Restrictions

Gelatin capsule used with a vegetarian formula.  Gelatin capsule used with a vegetarian formula.

References

  1. Hadley CW, Miller EC, Schwartz SJ, Clinton SK. Tomatoes, lycopene, and prostate cancer: progress and promise. Exp Biol Med ( Maywood). Nov 2002;227(10):869-880.
  2. Pastori M, Pfander H, Boscoboinik D, Azzi A. Lycopene in association with alpha-tocopherol inhibits at physiological concentrations proliferation of prostate carcinoma cells. Biochem Biophys Res Commun. 1998;250(3):582-585.
  3. Gann PH, Khachik F. Tomatoes or lycopene versus prostate cancer: is evolution anti-reductionist? J Natl Cancer Inst. Nov 5 2003;95(21):1563-1565.
  4. Etminan M, Takkouche B, Caamano-Isorna F. The role of tomato products and lycopene in the prevention of prostate cancer: a meta-analysis of observational studies. Cancer Epidemiol Biomarkers Prev. Mar 2004;13(3):340-345.
  5. Giovannucci E, Ascherio A, Rimm EB, Stampfer MJ, Colditz GA, Willett WC. Intake of carotenoids and retinol in relation to risk of prostate cancer. J Natl Canc Inst. 1995;87:1767-1776.
  6. Chen L, Stacewicz-Sapuntzakis M, Duncan C, et al. Oxidative DNA damage in prostate cancer patients consuming tomato sauce-based entrees as a whole-food intervention. J Natl Cancer Inst. 2001;93(24):1872-1879.
  7. Chan JM, Stampfer MJ, Giovannucci E, et al. Plasma insulin-like growth factor-I and prostate cancer risk: A prospective study. Science. 1998;279:563-566.
  8. Millen AE, Tucker MA, et. Al. Diet and Melanoma in a Case Control Study, Cancer Epidemiol Biomarkers Prev. 2004 Jun;13(6):1042-51.
  9. Nkondjock A, Ghadirian P.. Dietary carotenoids and risk of colon cancer: case-control study. Int J Cancer 2004 May 20;110(1):110-6.
  10. Murtaugh MA, Ma KN, et al. Antioxidants, carotenoids, and risk of rectal cancer. Am J Epidemiol . 2004 Jan 1;159(1):32-41.
  11. Kohlmeier L, Kark JD, GomezGracia E, et al. Lycopene and myocardial infarction risk in the EURAMIC Study. Am J Epidemiol. 1997;146:618-626 12. Truswell AS. ABC of nutrition. Nutrition for pregnancy. Br Med J 1985;291:263-6.
  12. Klipstein-Grobusch K, Launer LJ, Geleijnse JM, Boeing H, Hofman A, Witteman JC. Serum carotenoids and atherosclerosis. The Rotterdam Study. Atherosclerosis. 2000;148(1):49-56.
  13. Rissanen TH, Voutilainen S, Nyyssonen K, et al. Low serum lycopene concentration is associated with an excess incidence of acute coronary events and stroke: the Kuopio Ischaemic Heart Disease Risk Factor Study. Br J Nutr. 2001;85(6):749-754.
  14. Rissanen TH, Voutilainen S, Nyyssonen K, Salonen R, Kaplan GA, Salonen JT. Serum lycopene concentrations and carotid atherosclerosis: the Kuopio Ischaemic Heart Disease Risk Factor Study. Am J Clin Nutr. Jan 2003;77(1):133-138.
  15. Kristenson M, Zieden B, Kucinskiene Z, et al. Antioxidant state and mortality from coronary heart disease in Lithuanian and Swedish men: concomitant cross sectional study of men aged 50. BMJ. 1997;314(7081):629-633.
  16. Sesso HD, Buring JE, Norkus EP, Gaziano JM. Plasma lycopene, other carotenoids, and retinol and the risk of cardiovascular disease in women. Am J Clin Nutr. Jan 2004;79(1):47-53.
  17. Sesso HD, Liu S, Gaziano JM, Buring JE. Dietary lycopene, tomato-based food products and cardiovascular disease in women. J Nutr. Jul 2003;133(7):2336-2341
  18. Wood N, Johnson RB. The relationship between tomato intake and congestive heart failure risk in periodontitis subjects.J Clin Periodontol. 2004 Jul;31(7):574-80.
  19. Hak, A. Stroke: Journal of the American Heart Association, June 4, 2004; vol 35. News release, American Heart Association.
  20. Hak AE, Ma J, , et al. Prospective Study of Plasma Carotenoids and Tocopherols in Relation to Risk of Ischemic Stroke , Stroke . 2004 Jun 3.
  21. Xu Y, Leo MA, Lieber CS. Lycopene attenuates alcoholic apoptosis in HepG2 cells expressing CYP2E1. Biochem Biophys Res Commun. 2003 Aug 29;308(3):614-8.
  22. Simonelli F, Zarrilli F, Mazzeo S. Serum oxidative and antioxidant parameters in a group of Italian patients with age-related maculopathy. . Clin Chim Acta. 2002 Jun;320(1-2):111-5.
  23. Chew BP, Park JS. Carotenoid action on the immune response . J Nutr. 2004 Jan;134(1):257S-261S.
  24. Fuhrman B, Elias, A, et. al. Hypocholesterolemic effect of lycopene and beta-carotene is related to suppression of cholesterol synthesis and augmentation of LDL receptor activity in macrophages. Biochem Biophys Res Commun 1997; 233:658-662.
  25. Drs. Keith Ingold and Graham Burton. National Research Council of Canada.
  26. Venket Rao, Department of Nutritional Sciences, Faculty of Medicine, University of Toronto.


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