Myristin Cetyl Myristoleate CMO

 

Myristin Cetyl Myristoleate Discovery and History
CM was discovered by Harry W. Diehl, then of Rockville, Maryland, working alone in his home lab. Diehl was a chemistry researcher employed for forty years at the National Institutes of Health in Bethesda, MD. Some books, articles, and marketing literature have made too many misstatements about the discovery and history of CM to clarify in this report, but a few facts will help. Diehl cites 1964 as the year in which he actually identified CM. CM was never an NIH project; therefore, NIH never provided or cut the funding for its research, as some sources have stated. Diehl's laboratory experiments on CM were published in the Journal of Pharmaceutical Sciences in March, 1994.


Harry Diehl obtained a U.S. patent for CM for rheumatoid arthritis in 1977. He next obtained a U.S. patent for CM for osteoarthritis in 1996.


Several distributors claim that their product is from a vegetable source. At the present time there are no vegetable-derived commodities or articles of commerce that contain commercially viable concentrations of myristoleic acid, a necessary ingredient in manufacture of CM. As a practical matter, CM is made by using the myristoleic acid from bovine sources, which are generally available and contain sufficient amounts of myristoleic acid. Anyone buying a CM product claimed to be from a vegetable source should demand incontrovertible proof of the vegetable source. lndependent laboratory analysis of CM products has demonstrated at least one CM product claimed to be from a vegetable source is actually Cetyl Myristate, which is from the saturated fatty acid, Myristic Acid. Myristic Acid is available in vegetable sources, but its cetyl ester demonstrated negligible benefits in laboratory experiments. If proof is given of vegetable source, the buyer must then be sure that the product is not Cetyl Myristate instead of Cetyl Myristoleate. Recently a national network marketing company has added a vegetable-derived form of Cetyl Myristate, and markets it as CM, so be wary. If they tell you it's from a rare tropical plant, ask them when sunflowers became rare and tropical!


CM as a dietary supplement offers great promise, but some of the claims being made for it are unjustified.

1. While most people do not need to continue taking CM indefinitely on a daily basis, one "protocol" is not all that will ever be needed. Like any other dietary substance, CM is excreted over time. For some people, that can be rather slow, but for others it could be more rapid. Whatever relief is brought by CM can be expected to last as short a period as three to four months or as long as five years without any additional amounts. Harry Diehl's problem was in remission from 1991 to 1996, when he needed additional amounts of CM. Other factors, such as exercise or exertion, initial absorption, quantity of CM used, and consumption of joint-aggravating substances such as caffeine play a role, too. Most people will need a repeat course in one to two years, depending on many factors.
2. Most of the healthcare professionals who are knowledgeable in dietary supplementation with CM think that a usage range of 10-15 grams of elemental CM per course is about right. However, some people have reported significant improvement with as little as 3-4 grams while others have used 20-30 grams in two courses.
3. CM does not work in all cases, but it does appear to have a positive effect in 60-75% of cases. To reach the higher percentages of the range, a synergistic capsule containing glucosamine, along with lecithin and lipase for absorption, is required.