Back Back

Vitamin C
IN STOCK - YES

Vitamin C



What Is Vitamin C?

Vitamin C appears to be the most important antioxidant in hindering the oxidization process of LDL (bad) cholesterol. Hinder that process and you may hinder cardiovascular disease (“CVD”). Since CVD is the number one killer of Americans, hindering CVD is a worthy goal in its own right. But there is so much more that Vitamin C does. Vitamin C supplementation:
  • Can lower the incidence of cardiovascular disease; 3,5-8,10,13-19,27,48,49,50,60
  • Improves overall capillary health; 1,2
  • Improves overall immunity; 41,42,43
  • Improves athletic recovery; 32,33,34,35,36,47
  • Helps keep blood pressure low; 11,12,13
  • Improves wound healing; 1,2,56-63
  • Helps you battle Glaucoma; 69-71
  • Helps you ward off infections; 1,2
  • And much more.
So with all these benefits, why the extra ingredients? Because Vitamin C needs to be fully absorbed and distributed within your body and done in such a way that it does not cause damage. Our Super C™ formula takes that into account.

Why Is Our Vitamin C Better?

We offer two popular stand-alone Vitamin C products: time-released and pH-neutral products. Additionally, our Cardio C-Q10 Heart Complex contains vitamin C, all of our nine multivitamins contain at least 100% of the recommended daily intake value for vitamin C, and the very popular VitaBev Effervescent Multivitamin Drink contains 565mg (942% Daily Value) of Vitamin C per serving.


Related Articles



Vitamin C, SuperC™ Sustained Release, with Bioflavonoids, (90 tablets)   VC1   (90 Day Supply)
Vitamin C, SuperC™ Sustained Release, with Bioflavonoids, (90 tablets)
       
Retail
Normal 1 to 2 Price
Buy 1 to 5
$29.95
$11.98
$9.58
$8.98
It's SUPER WEEK!

Quantity:     Frequency: 


Vitamin C, Fully-Buffered with Bioflavonoids, 700mg (60 capsules)   VC7   (15-60 Day Supply)
Vitamin C, Fully-Buffered with Bioflavonoids, 700mg (60 capsules)
       
Retail
Normal 1 to 2 Price
Buy 1 to 5
$29.95
$11.98
$9.58
$8.98
It's SUPER WEEK!

Quantity:     Frequency: 

Additional Vitamin C Products we Carry


How Vitamin C Works


Most of us have heard of scurvy--the disease resulting from a lack of Vitamin C--it was first discovered in sailors who stayed out at sea for long periods of time without citrus fruits to eat; to address this, sailors started carrying limes with them to eat, and were consequently nicknamed "limies". One of the first symptoms of scurvy is bleeding gums, caused by weakened blood vessel walls. If the Vitamin C deficiency is left to persist, the scurvy victim will eventually die of internal and external bleeding--the blood vessels dissolve and fall apart, resulting in death. This happens because without Vitamin C, the body cannot produce collagen--the structural element in the body. Without collagen, the skin sags, the blood vessels weaken and leak, and bones and connective tissues weaken. Collagen is to the body what iron rebar is to concrete (collagen is actually stronger on an ounce-for-ounce basis than iron)!

(Additionally, your body needs sulfur to produce collagen. Please be sure to read about MSM, an organic, absorbable form of dietary sulfur.)

Is Heart Disease Chronic Vitamin C Deficiency?


According to researchers at the Linus Pauling Institute, heart disease and stroke are symptoms of a Vitamin C deficiency, also known as Scurvy!2,3 Strange as it may sound, the evidence supporting their hypothesis is compelling. We present it here, for educational purposes, because it is so interesting.

According to their hypothesis, degenerative heart disease is chronic low-grade scurvy.2 It is the "chronic" part--the fact that this deficiency occurs slowly over time--that leads to atherosclerotic plaques. Cholesterol is put there on your blood vessel wall by the body as a repair mechanism--it is the body's attempt to seal a crack or weak spot that has resulted from an inability of the body to produce the strengthening collagen, which in turn is the result of a Vitamin C deficiency.

Cholesterol, the substance of which atherosclerotic plaques are made, is not by itself dangerous (it is, in fact, what your brain is made of). It is the presence of oxidized cholesterol on the arterial walls that is dangerous, because as it builds up on the walls of the arteries, the diameter of the vessel wall is constricted, placing greater and greater strain on the heart in its effort to pump blood through the shrinking tube that is your blood vessel. Thus, according to their hypothesis, sufficient levels of Vitamin C would provide the body with the needed materials for collagen production, preventing cracks from developing in the vessel lining. This preempts the body's "cholesterol-patch" repair mechanism, preventing the accumulation of atherosclerotic plaques.


Label Facts

Vitamin C, SuperC™ Sustained Release, with Bioflavonoids, (90 tablets)

Supplement Facts
Serving Size: 1 Tablet
Servings per container: 90
Amount Per Serving % Daily Value
Vitamin C (as Calcium Ascorbate) 1000 mg 1670%
Calcium (as Calcium Ascorbate) 110 mg 11%
Citrus Bioflavonoids 250 mg
Acerola 50 mg
Rutin 50 mg
†Daily value not established.

   Other ingredients: Dicalcium phosphate, stearic acid (vegetable source), magnesium stearate (vegetable source).

Dietary Restrictions
This is a vegetarian product.  This is a vegetarian product.


Vitamin C, Fully-Buffered with Bioflavonoids, 700mg (60 capsules)

Supplement Facts
Serving Size: 1 Capsule
Servings per container: 60
Amount Per Serving % Daily Value
Vitamin C (from Calcium Ascorbate) 500 mg 833%
Calcium (from Calcium Ascorbate) 57 mg 6%
Citrus Bioflavonoids 200 mg
†Daily value not established.

   Other ingredients: Cellulose (plant fiber), stearic acid (vegtable source).

Dietary Restrictions
Vegetarian capsule used and a vegetarian formula.  Vegetarian capsule used and a vegetarian formula.


References

  1. Griffith , H. Winter, M.D. Vitamins, herbs, minerals and supplements: the complete guide 1998 Fisher Books, USA.
  2. Author Not Specified, The Physicians Desk Reference Family Guide To Natural Medicines And Healing TherapiesTM, 2000 Ballantine Books, a division of Random House, New York, New York.
  3. Fuller CJ, Grundy SM, Norkus EP, Jialal I. Effect of ascorbate supplementation on low density lipoprotein oxidation in smokers. Atherosclerosis. 1996 Jan 26;119(2):139-50.
  4. Cathcart RF 3rd. Vitamin C: the nontoxic, nonrate-limited, antioxidant free radical scavenger. Med Hypotheses. 1985 Sep;18(1):61-77 .
  5. Koscielny J, Klussendorf D, Latza R, Schmitt R, Radtke H, Siegel G, Kiesewetter H. The antiatherosclerotic effect of Allium sativum. Atherosclerosis 1999 May;144(1):237-49.
  6. Rath, M. and L. Pauling (1990). "Hypothesis: lipoprotein(a) is a surrogate for ascorbate [published erratum appears in Proc Natl Acad Sci U S A 1991 Dec 15;88(24):11588]." Proc Natl Acad Sci U S A 87(16): 6204-7.
  7. Rath, M. and L. Pauling (1990). "Immunological evidence for the accumulation of lipoprotein(a) in the atherosclerotic lesion of the hypoascorbemic guinea pig." Proc Natl Acad Sci U S A 87(23): 9388-90.
  8. Rath, M., A. Niendorf, T. Reblin, M. Dietel, H. J. Krebber and U. Beisiegel (1989). "Detection and quantification of lipoprotein(a) in the arterial wall of 107 coronary bypass patients [published erratum appears in Arteriosclerosis 1990 Nov-Dec;10(6):1147]." Arteriosclerosis 9(5): 579-92.
  9. Bsoul SA, Terezhalmy GT. Vitamin C in health and disease. J Contemp Dent Pract. 2004 May 15;5(2):1-13.
  10. Korantzopoulos P, Kolettis T, Siogas K, Goudevenos J. Atrial fibrillation and electrical remodeling: the potential role of inflammation and oxidative stress. Med Sci Monit. 2003 Sep;9(9):RA225-9.
  11. Chade AR, Rodriguez-Porcel M, Herrmann J, Krier JD, Zhu X, Lerman A, Lerman LO. Beneficial effects of antioxidant vitamins on the stenotic kidney. Hypertension. 2003 Oct;42(4):605-12. Epub 2003 Aug 18.
  12. Ohtsuka S, Yamazaki A, Oyake Y, Yamaguchi I. Amlodipine improves vascular function in patients with moderate to severe hypertension. J Cardiovasc Pharmacol. 2003 Aug;42(2):296-303
  13. Piccirillo G, Nocco M, Moise A, Lionetti M, Naso C, di Carlo S, Marigliano V. Influence of vitamin C on baroreflex sensitivity in chronic heart failure. Hypertension. 2003 Jun;41(6):1240-5. Epub 2003 May 12.
  14. Heitzer T, Schlinzig T, Krohn K, Meinertz T, Munzel T. Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation. 2001 Nov 27;104(22):2673-8.
  15. Singhal S, Gupta R, Goyle A. Comparison of antioxidant efficacy of vitamin E, vitamin C, vitamin A and fruits in coronary heart disease: a controlled trial. J Assoc Physicians India. 2001 Mar;49:327-31.
  16. Brown DJ, Goodman J. A review of vitamins A, C, and E and their relationship to cardiovascular disease. Clin Excell Nurse Pract. 1998 Jan;2(1):10-22.
  17. Antoniades C, Tousoulis D, Tentolouris C, Toutouzas P, Stefanadis C. Oxidative stress, antioxidant vitamins, and atherosclerosis. From basic research to clinical practice. Herz. 2003 Nov;28(7):628-38.

     

  18. Mezzetti A, Guglielmi MD, Pierdomenico SD, Costantini F, Cipollone F, De Cesare D, Bucciarelli T, Ucchino S, Chiarelli F, Cuccurullo F, Romano F. Increased systemic oxidative stress after elective endarterectomy: relation to vascular healing and remodeling. Arterioscler Thromb Vasc Biol. 1999 Nov;19(11):2659-65.
  19. Osganian SK, Stampfer MJ, Rimm E, Spiegelman D, Hu FB, Manson JE, Willett WC. Vitamin C and risk of coronary heart disease in women. J Am Coll Cardiol. 2003 Jul 16;42(2):246-52.
  20. Macdonald HM, New SA, Golden MH, Campbell MK, Reid DM. Nutritional associations with bone loss during the menopausal transition: evidence of a beneficial effect of calcium, alcohol, and fruit and vegetable nutrients and of a detrimental effect of fatty acids. Am J Clin Nutr. 2004 Jan;79(1):155-65.
  21. Turan B, Can B, Delilbasi E. Selenium combined with vitamin E and vitamin C restores structural alterations of bones in heparin-induced osteoporosis. Clin Rheumatol. 2003 Dec;22(6):432-6. Epub 2003 Oct 31.
  22. Kaptoge S, Welch A, McTaggart A, Mulligan A, Dalzell N, Day NE, Bingham S, Khaw KT, Reeve J. Effects of dietary nutrients and food groups on bone loss from the proximal femur in men and women in the 7th and 8th decades of age. Osteoporos Int. 2003 Jun;14(5):418-28. Epub 2003 Apr 16.
  23. Hata M, Miyao M, Mizuno Y. Osteoporosis as a lifestyle-related disease. Nippon Rinsho. 2003 Feb;61(2):305-13.
  24. Schaafsma A, de Vries PJ, Saris WH. Delay of natural bone loss by higher intakes of specific minerals and vitamins. Crit Rev Food Sci Nutr. 2001 May;41(4):225-49.
  25. Weber P. The role of vitamins in the prevention of osteoporosis--a brief status report. Int J Vitam Nutr Res. 1999 May;69(3):194-7.
  26. Hall SL, Greendale GA. The relation of dietary vitamin C intake to bone mineral density: results from the PEPI study. Calcif Tissue Int. 1998 Sep;63(3):183-9.
  27. Ziegler D, Sohr CG, Nourooz-Zadeh J. Oxidative stress and antioxidant defense in relation to the severity of diabetic polyneuropathy and cardiovascular autonomic neuropathy. Diabetes Care. 2004 Sep;27(9):2178-83.
  28. Park HS, Lee YM. Effect of Vitamin C Supplementation on Blood Sugar and Antioxidative Status in Types II Diabetes Mellitus Patients Taehan Kanho Hakhoe Chi. 2003 Apr;33(2):170-8.
  29. Hirsch IB, Atchley DH, Tsai E, Labbe RF, Chait A. Ascorbic acid clearance in diabetic nephropathy. J Diabetes Complications. 1998 Sep-Oct;12(5):259-63.
  30. Cunningham JJ. The glucose/insulin system and vitamin C: implications in insulin-dependent diabetes mellitus. J Am Coll Nutr. 1998 Apr;17(2):105-8.
  31. Krawczuk-Rybak M, Peczynska J, Urban M. Usefulness of antioxidant vitamin supplementation in children and adolescents with newly diagnosed diabetes mellitus type I. Endokrynol Diabetol Chor Przemiany Materii Wieku Rozw. 1999;5(1):11-20.
  32. Kujala UM, Sarna S, Kaprio J. Use of medications and dietary supplements in later years among male former top-level athletes. Arch Intern Med. 2003 May 12;163(9):1064-8.
  33. Machefer G, Groussard C, Rannou-Bekono F, Zouhal H, Faure H, Vincent S, Cillard J, Gratas-Delamarche A. Extreme running competition decreases blood antioxidant defense capacity. J Am Coll Nutr. 2004 Aug;23(4):358-64.
  34. Aguilo A, Tauler P, Fuentespina E, Villa G, Cordova A, Tur JA, Pons A.J Am Coll Nutr. 2004 Aug;23(4):358-64. Antioxidant diet supplementation influences blood iron status in endurance athletes. Int J Sport Nutr Exerc Metab. 2004 Apr;14(2):147-60.
  35. Robson PJ, Bouic PJ, Myburgh KH. Antioxidant supplementation enhances neutrophil oxidative burst in trained runners following prolonged exercise. Int J Sport Nutr Exerc Metab. 2003 Sep;13(3):369-81.
  36. Tauler P, Aguilo A, Gimeno I, Fuentespina E, Tur JA, Pons A. Influence of vitamin C diet supplementation on endogenous antioxidant defences during exhaustive exercise. Pflugers Arch. 2003 Sep;446(6):658-64. Epub 2003 Jul 12.
  37. Moller P, Viscovich M, Lykkesfeldt J, Loft S, Jensen A, Poulsen HE. Vitamin C supplementation decreases oxidative DNA damage in mononuclear blood cells of smokers. Eur J Nutr. 2004 Jan 6;:1-8.
  38. Teramoto K, Daimon M, Hasegawa R, Toyoda T, Sekine T, Kawata T, Yoshida K, Komuro I. Acute effect of oral vitamin C on coronary circulation in young healthy smokers. Am Heart J. 2004 Aug;148(2):300-5.
  39. Wright ME, Mayne ST, Stolzenberg-Solomon RZ, Li Z, Pietinen P, Taylor PR, Virtamo J, Albanes D. Development of a comprehensive dietary antioxidant index and application to lung cancer risk in a cohort of male smokers. Am J Epidemiol. 2004 Jul 1;160(1):68-76.
  40. Castelao JE, Yuan JM, Gago-Dominguez M, Skipper PL, Tannenbaum SR, Chan KK, Watson MA, Bell DA, Coetzee GA, Ross RK, Yu MC. Carotenoids/vitamin C and smoking-related bladder cancer. Int J Cancer. 2004 Jun 20;110(3):417-23.
  41. de la Fuente M, Ferrandez MD, Burgos MS, Soler A, Prieto A, Miquel J. Immune function in aged women is improved by ingestion of vitamins C and E. Can J Physiol Pharmacol. 1998 Apr;76(4):373-80.
  42. Buzina-Suboticanec K, Buzina R, Stavljenic A, Farley TM, Haller J, Bergman-Markovic B, Gorajscan M. Ageing, nutritional status and immune response. Int J Vitam Nutr Res. 1998;68(2):133-41.
  43. Penn ND, Purkins L, Kelleher J, Heatley RV, Mascie-Taylor BH, Belfield PW. The effect of dietary supplementation with vitamins A, C and E on cell-mediated immune function in elderly long-stay patients: a randomized controlled trial. Age Ageing. 1991 May;20(3):169-74.
  44. Author Unknown, Accelerated remission of episodes of Herpes labialis in response to a bioflavonoid-ascorbate supplement. Nutr Rev. 1978 Oct;36(10):300-1.
  45. Terezhalmy GT, Bottomley WK, Pelleu GB. The use of water-soluble bioflavonoid-ascorbic acid complex in the treatment of recurrent herpes labialis. Oral Surg Oral Med Oral Pathol. 1978 Jan;45(1):56-62.
  46. White LA, Freeman CY, Forrester BD, Chappell WA. In vitro effect of ascorbic acid on infectivity of herpesviruses and paramyxoviruses. J Clin Microbiol. 1986 Oct;24(4):527-31.
  47. Yanai H, Morimoto M. Effect of ascorbate on serum lipids and urate metabolism during exhaustive training. Clin Sci (Lond). 2004 Jan;106(1):107-9.
  48. Milde J, Elstner EF, Grassmann J. Synergistic inhibition of low-density lipoprotein oxidation by rutin, gamma-terpinene, and ascorbic acid. Phytomedicine. 2004 Feb;11(2-3):105-13.
  49. Naziroglu M, Simsek M, Simsek H, Aydilek N, Ozcan Z, Atilgan R. The effects of hormone replacement therapy combined with vitamins C and E on antioxidants levels and lipid profiles in postmenopausal women with Type 2 diabetes. Clin Chim Acta. 2004 Jun;344(1-2):63-71.
  50. Palade F, Alexa ID, Azoicai D, Panaghiu L, Ungureanu G. Oxidative stress in atherosclerosis. Rev Med Chir Soc Med Nat Iasi. 2003 Jul-Sep;107(3):502-11.
  51. Shidfar F, Keshavarz A, Jallali M, Miri R, Eshraghian M. Comparison of the effects of simultaneous administration of vitamin C and omega-3 fatty acids on lipoproteins, apo A-I, apo B, and malondialdehyde in hyperlipidemic patients. Int J Vitam Nutr Res. 2003 May;73(3):163-70.
  52. Rezaian GR, Taheri M, Mozaffari BE, Mosleh AA, Ghalambor MA. The salutary effects of antioxidant vitamins on the plasma lipids of healthy middle aged-to-elderly individuals: a randomized, double-blind, placebo-controlled study. J Med Liban. 2002 Jan-Apr;50(1-2):10-3.
  53. Evans AT, Husain S, Durairaj L, Sadowski LS, Charles-Damte M, Wang Y. Azithromycin for acute bronchitis: a randomised, double-blind, controlled trial. Lancet. 2002 May 11;359(9318):1648-54.
  54. Tribastone AD. Azithromycin no more effective than vitamin C for acute bronchitis. J Fam Pract. 2002 Sep;51(9):783.
  55. Hunt C, Chakravorty NK, Annan G, Habibzadeh N, Schorah CJ. The clinical effects of vitamin C supplementation in elderly hospitalised patients with acute respiratory infections. Int J Vitam Nutr Res. 1994;64(3):212-9.
  56. Collins N. Adding vitamin C to the wound management mix. Adv Skin Wound Care. 2004 Apr;17(3):109-12.
  57. Kaplan B, Gonul B, Dincer S, Dincer Kaya FN, Babul A. Relationships between tensile strength, ascorbic Acid, hydroxyproline, and zinc levels of rabbit full-thickness incision wound healing. Surg Today. 2004;34(9):747-51.
  58. Jagetia GC, Rajanikant GK, Baliga MS, Rao KV, Kumar P. Augmentation of wound healing by ascorbic acid treatment in mice exposed to gamma-radiation. Int J Radiat Biol. 2004 May;80(5):347-54.
  59. MacKay D, Miller AL. Nutritional support for wound healing. Altern Med Rev. 2003 Nov;8(4):359-77.
  60. da Silva RR, de Oliveira TT, Nagem TJ, Pinto AS, Albino LF, de Almeida MR, de Moraes GH, Pinto JG. Hypocholesterolemic effect of naringin and rutin flavonoids Arch Latinoam Nutr. 2001 Sep;51(3):258-64.
  61. Russell L. The importance of patients' nutritional status in wound healing. Br J Nurs. 2001 Mar;10(6 Suppl):S42, S44-9.
  62. Yilmaz C, Erdemli E, Selek H, Kinik H, Arikan M, Erdemli B. The contribution of vitamin C to healing of experimental fractures. Arch Orthop Trauma Surg. 2001 Jul;121(7):426-8.
  63. Silverstein RJ, Landsman AS. The effects of a moderate and high dose of vitamin C on wound healing in a controlled guinea pig model. J Foot Ankle Surg. 1999 Sep-Oct;38(5):333-8.
  64. Sinclair S. Male infertility: nutritional and environmental considerations. Altern Med Rev. 2000 Feb;5(1):28-38.
  65. Schill WB, Kohn FM. Therapy of male subfertility. Wien Med Wochenschr. 1997;147(4-5):76-80.
  66. Luck MR, Jeyaseelan I, Scholes RA. Ascorbic acid and fertility. Biol Reprod. 1995 Feb;52(2):262-6.
  67. Dawson EB, Harris WA, Powell LC. Relationship between ascorbic acid and male fertility. World Rev Nutr Diet. 1990;62:1-26.
  68. Dawson EB, Harris WA, Rankin WE, Charpentier LA, McGanity WJ. Effect of ascorbic acid on male fertility. Ann N Y Acad Sci. 1987;498:312-23.
  69. Bartlett H, Eperjesi F. An ideal ocular nutritional supplement? Ophthalmic Physiol Opt. 2004 Jul;24(4):339-49.
  70. Head KA. Natural therapies for ocular disorders, part two: cataracts and glaucoma. Altern Med Rev. 2001 Apr;6(2):141-66.
  71. Baxter RC. Vitamin C and glaucoma. J Am Optom Assoc. 1988 Jun;59(6):438.
  72. Kurowska EM, Manthey JA. Hypolipidemic effects and absorption of citrus polymethoxylated flavones in hamsters with diet-induced hypercholesterolemia. J Agric Food Chem. 2004 May 19;52(10):2879-86.
  73. Kurowska EM, Manthey JA. Regulation of lipoprotein metabolism in HepG2 cells by citrus flavonoids. Adv Exp Med Biol. 2002;505:173-9.
  74. Cha JY, Cho YS, Kim I, Anno T, Rahman SM, Yanagita T. Effect of hesperetin, a citrus flavonoid, on the liver triacylglycerol content and phosphatidate phosphohydrolase activity in orotic acid-fed rats. Plant Foods Hum Nutr. 2001;56(4):349-58.
  75. Lee CH, Jeong TS, Choi YK, Hyun BH, Oh GT, Kim EH, Kim JR, Han JI, Bok SH. Anti-atherogenic effect of citrus flavonoids, naringin and naringenin, associated with hepatic ACAT and aortic VCAM-1 and MCP-1 in high cholesterol-fed rabbits.Biochem Biophys Res Commun. 2001 Jun 15;284(3):681-8.
  76. Shin YW, Bok SH, Jeong TS, Bae KH, Jeoung NH, Choi MS, Lee SH, Park YB. Hypocholesterolemic effect of naringin associated with hepatic cholesterol regulating enzyme changes in rats. Int J Vitam Nutr Res. 1999 Sep;69(5):341-7.
  77. Monforte MT, Trovato A, Kirjavainen S, Forestieri AM, Galati EM, Lo Curto RB. Biological effects of hesperidin, a Citrus flavonoid. (note II): hypolipidemic activity on experimental hypercholesterolemia in rat. Farmaco. 1995 Sep;50(9):595-9.
  78. Borradaile NM, Carroll KK, Kurowska EM. Regulation of HepG2 cell apolipoprotein B metabolism by the citrus flavanones hesperetin and naringenin. Lipids. 1999 Jun;34(6):591-8.
  79. Bok SH, Lee SH, Park YB, Bae KH, Son KH, Jeong TS, Choi MS. Plasma and hepatic cholesterol and hepatic activities of 3-hydroxy-3-methyl-glutaryl-CoA reductase and acyl CoA: cholesterol transferase are lower in rats fed citrus peel extract or a mixture of citrus bioflavonoids. J Nutr. 1999 Jun;129(6):1182-5.
  80. Lee SH, Park YB, Bae KH, Bok SH, Kwon YK, Lee ES, Choi MS. Cholesterol-lowering activity of naringenin via inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase and acyl coenzyme A:cholesterol acyltransferase in rats. Ann Nutr Metab. 1999;43(3):173-80.
  81. Wilcox LJ, Borradaile NM, de Dreu LE, Huff MW. Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP. J Lipid Res. 2001 May;42(5):725-34.
  82. Granados Loarca EA. Use of flavonoids (hesperidin) in the treatment of bleeding bladder varices Actas Urol Esp. 2003 Oct;27(9):732-4.
  83. Nelson EA. Healing venous ulcers without compression. J Tissue Viability. 2003 Oct;13(4):174-5.
  84. Danielsson G, Norgren L, Truedsson L, Andreasson A, Danielsson P, Nilsson A, Swartbol P. Flavonoid treatment in patients with healed venous ulcer: flow cytometry analysis suggests increased CD11b expression on neutrophil granulocytes in the circulation. Vasc Med. 2003 May;8(2):83-8.
  85. Coleridge Smith PD. From skin disorders to venous leg ulcers: pathophysiology and efficacy of Daflon 500 mg in ulcer healing. Angiology. 2003 Jul-Aug;54 Suppl 1:S45-50.
  86. MacKay D. Hemorrhoids and varicose veins: a review of treatment options. Altern Med Rev. 2001 Apr;6(2):126-40.
  87. Lin LC, Kuo YC, Chou CJ. Anti-herpes simplex virus type-1 flavonoids and a new flavanone from the root of Limonium sinense. Planta Med. 2000 May;66(4):333-6.
  88. Vynograd N, Vynograd I, Sosnowski Z. A comparative multi-centre study of the efficacy of propolis, acyclovir and placebo in the treatment of genital herpes (HSV). Phytomedicine. 2000 Mar;7(1):1-6
  89. Lin YM, Flavin MT, Schure R, Chen FC, Sidwell R, Barnard DL, Huffman JH, Kern ER.. Antiviral activities of biflavonoids. Planta Med. 1999 Mar;65(2):120-5.
  90. Barnard DL, Smee DF, Huffman JH, Meyerson LR, Sidwell RW. Barnard DL, Smee DF, Huffman JH, Meyerson LR, Sidwell RW. Antiherpesvirus activity and mode of action of SP-303, a novel plant flavonoid. Chemotherapy. 1993 May-Jun;39(3):203-11.
  91. Yura Y, Yoshida H, Sato M. Inhibition of herpes simplex virus replication by genistein, an inhibitor of protein-tyrosine kinase. Arch Virol. 1993;132(3-4):451-61.
  92. Amoros M, Simoes CM, Girre L, Sauvager F, Cormier M. Synergistic effect of flavones and flavonols against herpes simplex virus type 1 in cell culture. Comparison with the antiviral activity of propolis. J Nat Prod. 1992 Dec;55(12):1732-40.
  93. Hayashi K, Hayashi T, Morita N. Mechanism of action of the antiherpesvirus biflavone ginkgetin. Antimicrob Agents Chemother. 1992 Sep;36(9):1890-3.
  94. Knekt P, Kumpulainen J, Jarvinen R, Rissanen H, Heliovaara M, Reunanen A, Hakulinen T, Aromaa A. Flavonoid intake and risk of chronic diseases. Am J Clin Nutr. 2002 Sep;76(3):560-8.
  95. Cornish KM, Williamson G, Sanderson J. Quercetin metabolism in the lens: role in inhibition of hydrogen peroxide induced cataract. Free Radic Biol Med. 2002 Jul 1;33(1):63-70.
  96. McLauchlan WR, Sanderson J, Williamson G. Quercetin protects against hydrogen peroxide--induced cataract. Biochem Soc Trans. 1997 Nov;25(4):S581.
  97. Rosler KH, Goodwin RS, Mabry TJ, Varma SD, Norris J. Flavonoids with anti-cataract activity from Brickellia arguta. J Nat Prod. 1984 Mar-Apr;47(2):316-9.
  98. Galisteo M, Garcia-Saura MF, Jimenez R, Villar IC, Wangensteen R, Zarzuelo A, Vargas F, Duarte J. Effects of quercetin treatment on vascular function in deoxycorticosterone acetate-salt hypertensive rats. Comparative study with verapamil. Planta Med. 2004 Apr;70(4):334-41.
  99. Ibarra M, Moreno L, Vera R, Cogolludo A, Duarte J, Tamargo J, Perez-Vizcaino F. Effects of the flavonoid quercetin and its methylated metabolite isorhamnetin in isolated arteries from spontaneously hypertensive rats. Planta Med. 2003 Nov;69(11):995-1000.
  100. Nicolaides AN. From symptoms to leg edema: efficacy of Daflon 500 mg. Angiology. 2003 Jul-Aug;54 Suppl 1:S33-44.
  101. Aoi W, Niisato N, Miyazaki H, Marunaka Y. Flavonoid-induced reduction of ENaC expression in the kidney of Dahl salt-sensitive hypertensive rat. Biochem Biophys Res Commun. 2004 Mar 19;315(4):892-6.
  102. Duarte J, Perez-Palencia R, Vargas F, Ocete MA, Perez-Vizcaino F, Zarzuelo A, Tamargo J. Antihypertensive effects of the flavonoid quercetin in spontaneously hypertensive rats. Br J Pharmacol. 2001 May;133(1):117-24.
  103. Javorkova V, Pechanova O, Andriantsitohaina R, Vrbjar N. Effect of polyphenolic compounds on the renal Na+,K(+)-ATPase during development and persistence of hypertension in rats. Exp Physiol. 2004 Jan;89(1):73-81.
  104. Taubert D, Berkels R, Roesen R, Klaus W. Chocolate and blood pressure in elderly individuals with isolated systolic hypertension. JAMA. 2003 Aug 27;290(8):1029-30.
  105. Xue B, Li JX, Chen LB. Depressive effect of total flavonoid fraction of Asttragalus complanatus R. Br and its influence upon hemodynamics in SHR. Zhongguo Zhong Yao Za Zhi. 2002 Nov;27(11):855-8.
  106. Jouad H, Lacaille-Dubois MA, Lyoussi B, Eddouks M. Effects of the flavonoids extracted from Spergularia purpurea Pers. on arterial blood pressure and renal function in normal and hypertensive rats. J Ethnopharmacol. 2001 Jul;76(2):159-63.
  107. Christie S, Walker AF, Hicks SM, Abeyasekera S. Flavonoid supplement improves leg health and reduces fluid retention in pre-menopausal women in a double-blind, placebo-controlled study. Phytomedicine. 2004 Jan;11(1):11-7.
  108. Rotelli AE, Guardia T, Juarez AO, de la Rocha NE, Pelzer LE. Comparative study of flavonoids in experimental models of inflammation. Pharmacol Res. 2003 Dec;48(6):601-6.
  109. Nagamine I, Akiyama T, Kainuma M, Kumagai H, Satoh H, Yamada K, Yano T, Sakurai H. Effect of acerola cherry extract on cell proliferation and activation of ras signal pathway at the promotion stage of lung tumorigenesis in mice. J Nutr Sci Vitaminol ( Tokyo). 2002 Feb;48(1):69-72.
  110. DERSE PH, ELVEHJEM CA. Nutrient content of acerola, a rich source of vitamin C. J Am Med Assoc. 1954 Dec 18;156(16):1501.
  111. CLEIN NW. Acerola juice, the richest known source of vitamin C; a clinical study in infants. J Pediatr. 1956 Feb;48(2):140-5.
  112. BOWERS EF, KUBIK MM. VITAMIN C LEVELS IN OLD PEOPLE AND THE RESPONSE TO ASCORBIC ACID AND TO THE JUICE OF THE ACEROLA (MALPIGHIA PUNICIFOLIA L.). Br J Clin Pract. 1965 Mar;19:141-7.
  113. Motohashi N, Wakabayashi H, Kurihara T, Fukushima H, Yamada T, Kawase M, Sohara Y, Tani S, Shirataki Y, Sakagami H, Satoh K, Nakashima H, Molnar A, Spengler G, Gyemant N, Ugocsai K, Molnar J. Biological activity of barbados cherry (acerola fruits, fruit of Malpighia emarginata DC) extracts and fractions. Phytother Res. 2004 Mar;18(3):212-23.
  114. Wakabayashi H, Fukushima H, Yamada T, Kawase M, Shirataki Y, Satoh K, Tobe T, Hashimoto K, Kurihara T, Motohashi N, Sakagami H. Inhibition of LPS-stimulated NO production in mouse macrophage-like cells by Barbados cherry, a fruit of Malpighia emarginata DC. Anticancer Res. 2003 Jul-Aug;23(4):3237-41.
  115. Hayden RE, Paniello RC, Yeung CS, Bello SL, Dawson SM. The effect of glutathione and vitamins A, C, and E on acute skin flap survival. Laryngoscope. 1987 Oct;97(10):1176-9.


   1-866-381-7693
www.WholeHealth.com
This website and these statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Please consult a properly trained medical practitioner for medical advice.

Please read the Terms and Conditions of Using this Site. All Material at this site Copyright © 1997-2012
Whole Health Products, LLC All Rights Reserved.